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Genetics of Diabetes

Homeostasis of Diabetes

Diabetes can also happen when there's a failure of homeostatic regulation of glucose. Insulin resistance and insufficient insulin production combine to cause persistent hyperglycemia, which is the cause of this impairment. Given that hyperglycemia is a hallmark of diabetes, the identification of abnormalities in the brain's hormone- and nutrition-sensing pathways that control glucose homeostasis will provide insight into the primary factor that sustains this metabolic condition. The cellular and molecular processes of CNS hormone and nutrition sensing that regulate glucose homeostasis are covered in this review. Changes in glucose homeostasis may have an intergenerational impact on diabetes in kids. There's a chance that children of diabetic parents will inherit genetic predispositions to the ailment. Furthermore, the development of metabolic diseases in the progeny might be influenced by the intrauterine environment and lifestyle choices made during pregnancy. Dysregulatio
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